If you have huge trace file with the following trace
 kgnfs_flushmsg:4808: CH OUT of ORDER SEND m->order 197816641 ch->order -1 ch 0xa0d530640
 kgnfs_flushmsg:4808: CH OUT of ORDER SEND m->order 197816642 ch->order -1 ch 0xa0d530640
Seems like you are hitting below bug:
Bug 16542886 - HUGE TRACE FILES WITH DNFS ERROR MESSAGES
New OA Framework 12.2.6 Update 10 Now Available - Web-based content in Oracle E-Business Suite Release 12 runs on the Oracle Application Framework (also known as OA Framework, OAF, or FWK) user interface l...
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